Polymorphism of murine endogenous proviruses revealed by using virus class-specific oligonucleotide probes
نویسندگان
چکیده
منابع مشابه
High-resolution analysis of the human HLA-DR polymorphism by hybridization with sequence-specific oligonucleotide probes.
The human major histocompatibility complex class II antigens of the HLA-D are highly polymorphic, surface proteins essential in the cellular interactions necessary for an immune response. The analysis of this polymorphism is crucial for (i) histocompatibility matching for transplantation and (ii) understanding the association between HLA-D and certain important diseases. The polymorphism of cer...
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Gene expression analysis by means of high-density-oligonucleotide-array chips is based on the sequence specific binding of mRNA to oligonucleotide probes and its measurement using fluorescence labels. The sensitivity of a probe to detect a certain amount of target mRNA considerably varies among the about 400.000 probes, which are covalently attached to a typical Affymetrix chip. We present a mo...
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Although several imaging modalities are widely used for tumor imaging, none are tumor type-specific. Different types of cancer exhibit differential therapeutic responses, thus necessitating development of an imaging modality able to detect various tumor types with high specificity. To illustrate this point, CD30-specific oligonucleotide aptamer in vivo imaging probes were conjugated to the near...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1988
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.62.1.168-175.1988